THE IMPACT OF CLINICAL-TRIAL PROTOCOLS ON PATIENT-CARE SYSTEMS IN A LARGE CITY HOSPITAL - ACCESS FOR THE SOCIALLY DISADVANTAGED

Some Americans suffer a higher cancer incidence and mortality than tho se in mainstream American society, and, in general, do not enjoy the s ame health status. Black Americans, for example, have higher cancer in cidence and lower survival rates than do white Americans. To date, the re is no known genetic basis to account for the disparities in cancer incidence and outcome between these races. Controlling for socioeconom ic status greatly reduces, and sometimes nearly eliminates, the appare nt contrast in cancer mortality and incidence between ethnic groups. P overty clearly is associated with diminished access to health care, an increased incidence of cancer, and 10-15% lower 5-year survival rates . Diminished access often is manifested by low quality and inadequate continuity of health care, as well as insufficient access to methods o f disease detection, diagnosis, treatment, and rehabilitation. Poor pe ople tend to concentrate on day-today survival, often feel hopeless an d powerless, and may become socially isolated. It is more difficult to conduct cancer treatment trials in a population characterized by such dramatic socioeconomic and cultural differences. Lack of insurance an d lack of compliance become trial-limiting issues. This paper examines what must be done to tear down the economic and cultural barriers to prevention, early detection, and treatment of cancer.