BACTERICIDAL EFFECTS OF POVODINE-IODINE SOLUTION TO ORAL PATHOGENIC BACTERIA IN-VITRO

Seven species of periodontal pathogenic bacteria (Bacteroides gingival is, Bacteroides intermedius, Bacteroides melaninogenicus, Fusobacteriu m nucleatum, Actinobacillus actinomycetemcomitans, Capnocytophaga spp. , Eikenella corrodens) and two control species (Streptococcus intermed ius, Pseudomonas aeruginosa) were selected in order to study the bacte ricidal effects of 10% povodine-iodine (PVP-I) aqueous solution in vit ro. The PVP-I solution was diluted to 10, 20, 50, 100, 200, 400, 800, 1600, 3200, 6400 and 12800 x and contact times were 15, 30 and 60 seco nds. The strongest bactericidal effects on the seven periodontal patho genic bacteria and two control bacteria were seen at a dilution of 400 x and a contact time of 15 seconds. Based on these findings, we advoc ate a 0.25% solution of 10% aqueous PVP-I for oral mucosa and periodon tal pocket irrigation.