THE COMPLETE SEQUENCE OF A 6794BP SEGMENT LOCATED ON THE RIGHT ARM OFCHROMOSOME-II OF SACCHAROMYCES-CEREVISIAE - FINDING OF A PUTATIVE DUTPASE IN A YEAST

Authors
DOIGNON F BITEAU N AIGLE M CROUZET M
Citation
F. Doignon et al., THE COMPLETE SEQUENCE OF A 6794BP SEGMENT LOCATED ON THE RIGHT ARM OFCHROMOSOME-II OF SACCHAROMYCES-CEREVISIAE - FINDING OF A PUTATIVE DUTPASE IN A YEAST, Yeast, 9(10), 1993, pp. 1131-1137
Citations number
19
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology",Biology
Journal title
Yeast → ACNP
ISSN journal
0749503X
Volume
9
Issue
10
Year of publication
1993
Pages
1131 - 1137
Database
ISI
SICI code
0749-503X(1993)9:10<1131:TCSOA6>2.0.ZU;2-4
Abstract
The DNA sequence of a 6794 bp fragment located at about 100 kb from th e right telomere of chromosome II from Saccharomyces cerevisiae has be en determined. Sequence analysis reveals five open reading frames. One is the ARO4 gene encoding the 3-deoxy-D-arabinoheptulosonate 7-phosph ate synthase. Another presents strong homology with the S5 ribosomal p rotein from bacteria. The open reading frame YBR1705 shows significant homology with dUTPase, suggesting for the first time the existence of such an enzyme in S. cerevisiae.