A CIRCADIAN DISTRIBUTION TO FEBRILE EPISODES IN NEUTROPENIC PATIENTS

Authors
MAHER J BROWNE P DALY L MCCANN SR DALY PA
Citation
J. Maher et al., A CIRCADIAN DISTRIBUTION TO FEBRILE EPISODES IN NEUTROPENIC PATIENTS, Supportive care in cancer, 1(2), 1993, pp. 98-100
Citations number
12
Categorie Soggetti
Oncology,Rehabilitation,"Medicine, General & Internal
Journal title
Supportive care in cancer → ACNP
ISSN journal
09414355
Volume
1
Issue
2
Year of publication
1993
Pages
98 - 100
Database
ISI
SICI code
0941-4355(1993)1:2<98:ACDTFE>2.0.ZU;2-W
Abstract
Four-hourly temperature charts relating to 63 febrile neutropenic epis odes in 32 patients were assessed for a circadian distribution to the onset of fever (>37.5-degrees-C) using the Edward's test. A highly sig nificant distribution was found with the maximum incidence of febrile events between the hours of 5 p.m. and midnight (acrophase 9.30 p.m.). Patients were 5.53 times more likely to develop fever at 9.30 p.m. th at 9.30 a.m.