J. Reisch et al., ACETYLENE CHEMISTRY .25. REACTIONS OF ETHYL 4-HYDROXY-3-QUINOLIN-2(1H)-ONECARBOXYLATES WITH 3-BROMOPROP-1-YNE, Journal of heterocyclic chemistry, 30(4), 1993, pp. 861-863
Ethyl 4-hydroxyquinolin-2(1H)-onecarboxylates 1a and 1b which are obta
ined conveniently by the condensation of isatoic anhydride and diethyl
malonate [4], were reacted with 3-bromoprop-1-yne (2) to obtain mono-
and dialkylated derivatives.