J. Reisch et al., NATURAL PRODUCT CHEMISTRY .158. REACTIONS OF ETHYL 4-HYDROXY-1-METHYL-3-QUINOLIN-2(1H)-ONECARBOXYLATE WITH 1,4-DIBROMO-2-METHYL-2-BUTENE, Journal of heterocyclic chemistry, 30(4), 1993, pp. 977-979
Ethyl 4-hydroxy-1-methyl-3-quinolin-2(1H)-onecarboxylate (1) which is
obtained conveniently by the condensation of N-methylisatoic anhydride
with diethyl malonate [4], was reacted with 1,4-dibromo-2-methyl-bute
ne (2) to give the main products 3 and 4 and the dimeric derivatives 5
and 6.