POLYCYCLIC N-HETEROCYCLIC COMPOUNDS .44. SYNTHESIS OF THE NOVEL B,D-DIHOMO-11,13,15-TRIAZASTEROIDAL SKELETON AND THEIR EFFECT ON RESERPINE-INDUCED HYPOTHERMIA AND INHIBITORY ACTIVITY ON PLATELET-AGGREGATION

Authors
SASAKI K ARIMOTO Y OHTOMO H NAKAYAMA T HIROTA T
Citation
K. Sasaki et al., POLYCYCLIC N-HETEROCYCLIC COMPOUNDS .44. SYNTHESIS OF THE NOVEL B,D-DIHOMO-11,13,15-TRIAZASTEROIDAL SKELETON AND THEIR EFFECT ON RESERPINE-INDUCED HYPOTHERMIA AND INHIBITORY ACTIVITY ON PLATELET-AGGREGATION, Journal of heterocyclic chemistry, 30(4), 1993, pp. 989-992
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
30
Issue
4
Year of publication
1993
Pages
989 - 992
Database
ISI
SICI code
0022-152X(1993)30:4<989:PNC.SO>2.0.ZU;2-2
Abstract
Synthesis of o[3,4]cyclohepta[1,2-e]pyrimido[1,2-c]pyrimidines, corres ponding to the B,D-dihomo-11,13,15-triazasteroidal skeleton as a novel ring system is described. Their effects on reserpine-induced hypother mia in mice and inhibitory activity against collagen-induced platelet aggregation were also investigated.