ALKYLATION OF QUINAZOLINE-2,4(1H,3H)-DIONES WITH 1,4-DIBROMO-2-METHYYLBUT-2-ENE UNDER PHASE-TRANSFER-CATALYSIS

Authors
REISCH J IDING M USIFOH CO
Citation
J. Reisch et al., ALKYLATION OF QUINAZOLINE-2,4(1H,3H)-DIONES WITH 1,4-DIBROMO-2-METHYYLBUT-2-ENE UNDER PHASE-TRANSFER-CATALYSIS, Journal of heterocyclic chemistry, 30(4), 1993, pp. 1117-1120
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
30
Issue
4
Year of publication
1993
Pages
1117 - 1120
Database
ISI
SICI code
0022-152X(1993)30:4<1117:AOQW1>2.0.ZU;2-F
Abstract
Quinazoline-2,4(1H,3H)-dione (1) was reacted with 1,4-dibromo-2-methyl but-2-ene (2) to give two dialkylated products and two monoalkylated p roducts. The reaction of 6,7-dimethoxyquinazoline-2,4(1H,3H)-dione (8) with 1,4-dibromo-2-methylbut-2-ene (2) resulted in the formation of t hree dialkylated products.