SYNTHESIS OF THROMBOXANE-B(3) AND ITS DIRECT SEPARATION FROM THROMBOXANE-B(2) BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Authors
NAKAMURA N NAGAI H YONEDA M SUGA H KAWAMURA M IGUCHI S
Citation
N. Nakamura et al., SYNTHESIS OF THROMBOXANE-B(3) AND ITS DIRECT SEPARATION FROM THROMBOXANE-B(2) BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Chemical and Pharmaceutical Bulletin, 41(10), 1993, pp. 1769-1773
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
41
Issue
10
Year of publication
1993
Pages
1769 - 1773
Database
ISI
SICI code
0009-2363(1993)41:10<1769:SOTAID>2.0.ZU;2-Q
Abstract
The first chemical synthesis of thromboxane B3 starting with the Corey lactone is described. A reversed-phase high-performance liquid chroma tographic method was developed for the direct determination without de rivatization, of thromboxane B3 in the presence of thromboxane B2.