Mr. Meselhy et al., 2 NEW QUINOCHALCONE YELLOW PIGMENTS FROM CARTHAMUS-TINCTORIUS AND CA2+ ANTAGONISTIC ACTIVITY OF TINCTORMINE, Chemical and Pharmaceutical Bulletin, 41(10), 1993, pp. 1796-1802
Two new quinochalcone C-glycosides, hydroxysafflor yellow A (1a) and t
inctormine (2a), were isolated from Carthamus tinctorius L.(Compositae
) together with carthamin, safflor yellow B and safflomin C. The struc
tures of 1a and 2a have been determined by spectroscopic methods inclu
ding heteronuclear multiple-bond multiple-quantum coherence and linked
scan FAB-MS. The latter compound (2a) was demonstrated to have potent
Ca2+ antagonistic action.