ORAL SQUAMOUS-CELL CARCINOMA FOLLOWING TREATMENT OF ACUTE LYMPHOBLASTIC-LEUKEMIA

With substantially increased survival after most paediatric cancers ov er the past decades have come the late sequelae of treatment. Of all l ate complications of treatment, second malignancies are generally cons idered to be the most serious. We report on a 20-year-old man with an oral squamous cell carcinoma 17 years after initial chemotherapy and i rradiation for acute lymphoblastic leukaemia. Although occurrence of t he oral malignancy in this patient could have been treatment-related, one should keep in mind that the occurrence of second tumours may also be based on a shared genetic aetiology.