PURPOSE: To evaluate the long-term results of recanalization of occlud
ed iliac arteries with local low-dose thrombolysis, angioplasty, and,
if necessary, stent implantation. MATERIALS AND METHODS: Forty-seven p
atients with acute or chronic occlusions of the common or external ili
ac artery, or both, underwent local low-dose thrombolysis (n = 47), pe
rcutaneous transluminal angioplasty (PTA) (with balloon dilation [n =
43] and rotational angioplasty [n = 30] in the patients in whom a retr
ograde recanalization was performed), and, if needed, intravascular st
ent placement (n = 18). Follow-up lasted 3-53 (mean, 21) months. RESUL
TS: The primary recanalization rate was 98% (46 of 47). The mean ankle
-brachial index increased from 0.33 to 0.81 within 14 days after treat
ment and was 0.76 at the most recent follow-up. Two early (< 14 days)
and two late reocclusions (after 24 and 30 months) occurred; one reste
nosis detected with duplex sonography and angiography was observed aft
er 19 months. CONCLUSION: This therapy represents a true alternative t
o vascular surgery and a first-line treatment for acute or chronically
occluded iliac arteries.