J. Chin et al., MAGIC-ANGLE-SPINNING NMR FOR REACTION MONITORING AND STRUCTURE DETERMINATION OF MOLECULES ATTACHED TO MULTIPIN CROWNS, Journal of organic chemistry, 62(3), 1997, pp. 538-539
The first example of magic angle spinning NMR on crowns has been demon
strated. The ability to monitor a reaction on a crown and to confirm t
he structure of the reaction product directly on the crown without res
orting to chemical cleavage should greatly enhance the utility of this
convenient format for combinatorial chemistry.