PRIMARY PAPILLARY PSAMMOMATOUS ADENOCARCINOMA OF THE UMBILICUS

The histological and ultrastructural features, as well as the immunore activity of one case of uncommon primary papillary and psammomatous ad enocarcinoma of the umbilicus are studied in the present work. The obs ervations have been undertaken in a nine-year follow-up, and have incl uded the primitive tumour, two local recidives, and inguinal lymphatic metastasis on two occasions. Papillary structures, numerous psammoma bodies, as well as weak and focal positive reactions to CEA and cytoke ratin were present in all the tumours. Since these features and their ultrastructural characteristics were identical to primary papillary se rous neoplasias of the peritoneum and ovarium, the hypothesis of an or igin in coelomic remnants is considered.