Db. Hoyt et al., A RISK ANALYSIS OF PULMONARY COMPLICATIONS FOLLOWING MAJOR TRAUMA, The journal of trauma, injury, infection, and critical care, 35(4), 1993, pp. 524-531
Varying institutional definitions and degrees of surveillance limit aw
areness of the true incidence of posttraumatic pulmonary complications
. Prospective review with standardized definitions of 25 categories of
pulmonary complications was applied to a university level I trauma se
rvice over 3 years to establish the true incidence. Potential injury-r
elated predictors of individual complications were determined using mu
ltiple logistic regression analysis and adjusted odds ratios were calc
ulated, thereby controlling for the effect of other covariants. Signif
icance was attributed to p < 0.05. Of 3289 patients meeting MTOS crite
ria, pulmonary complications occurred in 368 (11.2%). Pulmonary compli
cations account for one third of all disease complications. Significan
t associations with pneumonia included age, the presence of shock on a
dmission, significant head injury, and surgery to the head and chest.
Significant risk for atelectasis occurred in patients with blunt injur
y mechanism, ISS > 16, shock on admission, and severe head injury. Ris
ks for development of respiratory failure included age > 55 years, the
mechanism of ''pedestrian struck'', and the presence of significant h
ead injury. Risk factors for ARDS included surgery to the head and a T
rauma Score < 13 on arrival. Significant predictors for pulmonary embo
lism included ISS > 16, shock on admission, and extremity and pelvis i
njuries. The true incidence of pulmonary complications is established
with this kind of analysis and focuses attention on (1) groups at high
risk for developing complications, (2) groups for Which current thera
peutic modalities are still ineffective, and (3) defining the need to
refocus on prospective research rather than ineffective processes of c
are.