A FACILE ONE-POT SYNTHESIS OF 5-TRIFLUOROMETHYLOXAZOLES AND 5-PERFLUOROALKYLOXAZOLES FROM N-ALKYL-N-ACYLAMINO ACIDS

Authors
KAWASE M
Citation
M. Kawase, A FACILE ONE-POT SYNTHESIS OF 5-TRIFLUOROMETHYLOXAZOLES AND 5-PERFLUOROALKYLOXAZOLES FROM N-ALKYL-N-ACYLAMINO ACIDS, Heterocycles, 36(11), 1993, pp. 2441-2444
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
36
Issue
11
Year of publication
1993
Pages
2441 - 2444
Database
ISI
SICI code
0385-5414(1993)36:11<2441:AFOSO5>2.0.ZU;2-B
Abstract
The reaction of N-acyl-N-benzyl-alpha-amino acids with trifluoroacetic or perfluorocarboxylic anhydride in the presence of pyridine affords 5-trifluoromethyl- or 5-perfluoroalkyloxazoles in high yields.