CLONING, EXPRESSION AND SEQUENCE-ANALYSIS OF CDNA FOR THE CA2-BINDINGPHOTOPROTEIN, MITROCOMIN()

Authors
FAGAN TF OHMIYA Y BLINKS JR INOUYE S TSUJI FI
Citation
Tf. Fagan et al., CLONING, EXPRESSION AND SEQUENCE-ANALYSIS OF CDNA FOR THE CA2-BINDINGPHOTOPROTEIN, MITROCOMIN(), FEBS letters, 333(3), 1993, pp. 301-305
Citations number
29
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
333
Issue
3
Year of publication
1993
Pages
301 - 305
Database
ISI
SICI code
0014-5793(1993)333:3<301:CEASOC>2.0.ZU;2-3
Abstract
The primary structure of mitrocomin consists of 190 amino acid residue s, with three Ca2+-binding sites and a tyrosine residue at tbe C-termi nus. Mitrocomin shows an amino acid sequence homology of 67.9% and 60. 7% when compared with aequorin and clytin, respectively. The amino aci d residues Cys152, His58, His169, Trp12, Trp86, Trp108, Trp129 and Trp 173 are conserved in all three photoproteins, suggesting that they pla y a role in light emission.