NEURON-SPECIFIC ENOLASE - A SERUM TUMOR-MARKER IN RENAL-CELL CARCINOMA

In previous reports, neuron-specific enolase (NSE) has been considered to be a useful tumor marker in renal cell carcinoma (RCC). This led u s to perform a prospective clinical trial in this field. NSE was check ed as a tumor marker for diagnosis and monitoring of patients with RCC . We report on 55 patients and their NSE level before and after radica l nephrectomy and correlated the serum level of NSE to immunohistologi cal staining and clinical stage of nephrectomy specimens. In contrast to other researchers, our results on NSE as a tumor marker in RCC are disappointing.