INCREASED SUSCEPTIBILITY OF PSEUDOMONAS-AERUGINOSA TO CIPROFLOXACIN IN THE PRESENCE OF VANCOMYCIN

Authors
DAY CA MARCEAUDAY ML DAY DF
Citation
Ca. Day et al., INCREASED SUSCEPTIBILITY OF PSEUDOMONAS-AERUGINOSA TO CIPROFLOXACIN IN THE PRESENCE OF VANCOMYCIN, Antimicrobial agents and chemotherapy, 37(11), 1993, pp. 2506-2508
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
37
Issue
11
Year of publication
1993
Pages
2506 - 2508
Database
ISI
SICI code
0066-4804(1993)37:11<2506:ISOPTC>2.0.ZU;2-#
Abstract
Vancomycin in combination with ciprofloxacin exhibited synergy against 7 of 10 strains of Pseudomonas aeruginosa. MICs for the microbial str ains used in this study ranged from 0.0325 to 3.0 mug/ml for ciproflox acin and from 23.5 to >188 mug/ml for vancomycin. Combinations of thes e antibiotics, tested in a checkerboard pattern, gave fractional inhib itory concentrations of 0.5 or less for 7 of the 10 strains tested.