TREATMENT OF PRIMARY GLOMERULONEPHRITIS W ITH A NEPHROTIC SYNDROME IN1993

Immunosuppressive treatment of rapidly progressive glomerulonephritis is indicated in almost all cases, while patients with the idiopathic n ephrotic syndrome are often treated without a clear-cut indication. Ge nerally accepted are corticosteroids for minimal-change nephropathy an d the combination of corticosteroids and chlorambucil for membranous g lomerulonephritis. Immunosuppression as a treatment of all other forms of the idiopathic nephrotic syndrome is not established, because of t he lack of conclusive controlled clinical studies. Nevertheless, there might be an indication to treat certain severe cases, which should be regarded as experimental, but sustained by case reports.