EFFECT OF INOCULUM SIZE ON ANTIMICROBIAL SUSCEPTIBILITY OF HELICOBACTER-PYLORI

Authors
BERGER SA GOREA A MOSKOWITZ M SANTO M GILAT T
Citation
Sa. Berger et al., EFFECT OF INOCULUM SIZE ON ANTIMICROBIAL SUSCEPTIBILITY OF HELICOBACTER-PYLORI, European journal of clinical microbiology & infectious diseases, 12(10), 1993, pp. 782-783
Citations number
12
Categorie Soggetti
Immunology,Microbiology
Journal title
European journal of clinical microbiology & infectious diseases → ACNP
ISSN journal
09349723
Volume
12
Issue
10
Year of publication
1993
Pages
782 - 783
Database
ISI
SICI code
0934-9723(1993)12:10<782:EOISOA>2.0.ZU;2-8
Abstract
An agar dilution assay was used to assess the effect of inoculum size and culture period on the susceptibility of 15 clinical isolates of He licobacter pylori to ampicillin, erythromycin, tetracycline, chloramph enicol, metronidazole and tinidazole. The mean MIC of the isolates inc reased 2.2- to 21.2-fold as the inoculum size progressed from 10(3) to 10(7) cfu/spot. Identical results were noted when isolates were maint ained for two or four days prior to testing. Inoculum size should be c arefully controlled when assessing the in vitro susceptibility of Heli cobacter pylori.