KALMAN FILTERING OF DATA FROM 1ST-ORDER AND 2ND-ORDER KINETICS

The Kalman filter algorithm was used to process data obtained in the s imultaneous determination of species following first- and second-order kinetics. The performance of the algorithm in the quantification of c hemical components from simulated data was assessed, and the influence of various parameters involved was estimated. The algorithm was appli ed to the resolution of cysteine-ascorbic acid and glutathione-ascorbi c acid mixtures where the ascorbic acid followed pseudo first-order ki netics and the amino acids second-order kinetics in the reaction with the copper(II)-neocuproine system. Some features of the determinations (namely, afforded concentration ratios, accuracy and precision) are d iscussed.