An 88-kDa component secreted in vitro by Aspergillus fumigatus has bee
n purified by sequential chromatographic procedures. The molecule is a
glycoprotein with an N-linked sugar moiety composed of mannose glucos
e, and galactose (16:10:1). It is recognized by antibodies from patien
ts with aspergilloma and has potential for the immunodiagnosis of aspe
rgilloma. The antigenicity is associated with the polypeptide part of
the molecule (79 kDa).