SYNTHESIS OF DIHYDROXY-4-BETA-CYCLOPENTANEMETHANOL-5-PHOSPHATE, A CARBOCYCLIC ANALOG OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP)

Authors
PARRY RJ HARIDAS K
Citation
Rj. Parry et K. Haridas, SYNTHESIS OF DIHYDROXY-4-BETA-CYCLOPENTANEMETHANOL-5-PHOSPHATE, A CARBOCYCLIC ANALOG OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP), Tetrahedron letters, 34(44), 1993, pp. 7013-7016
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
44
Year of publication
1993
Pages
7013 - 7016
Database
ISI
SICI code
0040-4039(1993)34:44<7013:SODAC>2.0.ZU;2-U
Abstract
5-Phosphoribosyl-1-pyrophosphate (PRPP) is a key intermediate in a var iety of important metabolic pathways. A total synthesis of the cyclope ntyl analog of PRPP has been accomplished. A formal total synthesis of the enantiomer of this analog whose absolute configuration correspond s to that of PRPP is also reported.