EFFECTS OF BUSPIRONE ON THE RESISTANCE, DEVELOPMENT AND PASSIVE TRANSFER OF IMMUNITY TO LISTERIA-MONOCYTOGENES IN MICE SUBMITTED TO STRESS

Authors
FREIREGARABAL M NUNEZ MJ FERNANDEZRIAL JC REYMENDEZ M BELMONTE A
Citation
M. Freiregarabal et al., EFFECTS OF BUSPIRONE ON THE RESISTANCE, DEVELOPMENT AND PASSIVE TRANSFER OF IMMUNITY TO LISTERIA-MONOCYTOGENES IN MICE SUBMITTED TO STRESS, Archives internationales de pharmacodynamie et de therapie, 324, 1993, pp. 114-123
Citations number
36
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archives internationales de pharmacodynamie et de therapie → ACNP
ISSN journal
00039780
Volume
324
Year of publication
1993
Pages
114 - 123
Database
ISI
SICI code
0003-9780(1993)324:<114:EOBOTR>2.0.ZU;2-A
Abstract
Mice exposed to a chronic auditory stressor and treated chronically wi th buspirone (I mg/kg) showed a reduction in stress-induced suppressio n of the resistance and development of immunity to Listeria monocytoge nes. Attempts to passively transfer immunity with spleen cells were al so performed. Stressed, immunized mice had a reduced capacity to trans fer immunity passively to nonimmunized mice and buspirone was found to partially suppress this inhibitory effect of stress.