LARGE SOMATOSTATIN-INSENSITIVE THYROTROPIN-SECRETING PITUITARY-TUMOR RESPONSIVE TO D-THYROXINE AND DOPAMINE AGONISTS

Authors
KARLSSON FA BURMAN P KAMPE O WESTLIN JE WIDE L
Citation
Fa. Karlsson et al., LARGE SOMATOSTATIN-INSENSITIVE THYROTROPIN-SECRETING PITUITARY-TUMOR RESPONSIVE TO D-THYROXINE AND DOPAMINE AGONISTS, Acta endocrinologica, 129(4), 1993, pp. 291-295
Citations number
18
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Acta endocrinologica → ACNP
ISSN journal
00015598
Volume
129
Issue
4
Year of publication
1993
Pages
291 - 295
Database
ISI
SICI code
0001-5598(1993)129:4<291:LSTPR>2.0.ZU;2-G
Abstract
A unique thyrotrophin (TSH)-secreting pituitary tumour is described in a patient with a history of recurrent thyrotoxicosis. Unlike other pr eviously reported TSHomas, the tumour is insensitive to octreotide, a somatostatin analogue. It does not accumulate [In-111]octreotide but e xpresses functional dopamine receptors and responds to the D-isomer of thyroxine, two characteristics beneficial in the management of the pa tient.