DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE ORAL TONGUE

Citation
Tw. Leung et al., DEFINITIVE RADIOTHERAPY FOR CARCINOMA OF THE ORAL TONGUE, Acta oncologica, 32(5), 1993, pp. 559-564
Citations number
33
Categorie Soggetti
Oncology
Journal title
ISSN journal
0284186X
Volume
32
Issue
5
Year of publication
1993
Pages
559 - 564
Database
ISI
SICI code
0284-186X(1993)32:5<559:DRFCOT>2.0.ZU;2-0
Abstract
This is a retrospective analysis of 117 patients with carcinoma of the oral tongue treated by definitive radiotherapy during 1979-1990. Sixt y-seven per cent of patients presented with T1-2 disease. Their cumula tive incidence of local failure was 10% (5/50) for those suitable for treatment with implant alone, 81% (13/16) for those treated with exter nal irradiation alone and 67% (8/12) after combined treatment. These d ifferences could largely be explained by selection factors as smaller and less bulky tumours generally were selected for implant treatment. Among the patients who achieved local control, there was no incidence of regional relapse (0/9) for those with elective neck irradiation, bu t 33% (15/46) for those without. This incidence correlated with size o f primary tumour. Radiotherapy achieved effective local control in 13% (5/39) of T3-4 tumours, and regional control in 43% (12/28) of N1-3 c ases. Only 32% (24/76) of patients with local and/or regional recurren ce were successfully salvaged. Ways of improving the treatment are dis cussed.