BRAIN METASTASIS FROM CLEAR-CELL SARCOMA OF THE KIDNEY - A CASE-REPORT AND REVIEW OF THE LITERATURE

Citation
Rl. Sahjpaul et al., BRAIN METASTASIS FROM CLEAR-CELL SARCOMA OF THE KIDNEY - A CASE-REPORT AND REVIEW OF THE LITERATURE, Journal of neuro-oncology, 16(3), 1993, pp. 221-226
Citations number
29
Categorie Soggetti
Neurosciences,Oncology
Journal title
ISSN journal
0167594X
Volume
16
Issue
3
Year of publication
1993
Pages
221 - 226
Database
ISI
SICI code
0167-594X(1993)16:3<221:BMFCSO>2.0.ZU;2-4
Abstract
We describe a 5 year old boy with a 5.5 cm right frontal lobe brain me tastasis from primary clear cell sarcoma of the kidney without evidenc e of tumor-associated edema or contrast enhancement on either computed tomography or magnetic resonance imaging. The metastasis regressed bu t did not disappear with chemotherapy and dexamethasone, and the resid ual tumor was removed surgically. On histological examination the majo rity of the tumor was composed of mature connective tissue with a rim of typical renal clear cell sarcoma cells at the brain-tumor interface . The avascular and desmoplastic nature of the metastasis may explain the unusual radiographic features. Brain metastases from this tumor ha ve only infrequently been reported; therefore a brief review of this r are tumor is provided.