ENANTIOSELECTIVITY OF ESTERASES IN HUMAN BRAIN

Authors
YANG SK HUANG A HUANG JD
Citation
Sk. Yang et al., ENANTIOSELECTIVITY OF ESTERASES IN HUMAN BRAIN, Chirality, 5(7), 1993, pp. 565-568
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chirality → ACNP
ISSN journal
08990042
Volume
5
Issue
7
Year of publication
1993
Pages
565 - 568
Database
ISI
SICI code
0899-0042(1993)5:7<565:EOEIHB>2.0.ZU;2-N
Abstract
Subcellular fractions of three human brain specimens were found to con tain esterase activities which hydrolyzed racemic oxazepam 3-acetate ( rac-OXA). All three human brain preparations were highly selective tow ard the S-enantiomer of rac-OXA. (C) 1993 Wiley-Liss, Inc.