DIAZALD, A NEWLY RECOGNIZED ANTIMICROBIAL AGENT AND ITS SPECTROPHOTOMETRIC DETERMINATION

Diazald, a chemical intermediate for the synthesis of biologically act ive compounds, was found to be a potent in vitro antimicrobial agent a gainst yeasts, yeast-like and filamentous fungi as well as Gram-positi ve and Gram-negative bacterial strains. Its activity is not inhibited by either para-aminobenzoic acid (PABA) or the nitroso group-specific 2-aminothiazole-methoxyimino acetic acid (ATMAA). This suggests that t he molecule as such is responsible for the antimicrobial activity. For its quick measurement a sensitive spectrophotometric method has been developed.