Ap. Gregoriou et al., PHENOBARBITAL-INDUCED GINGIVAL OVERGROWTH - REPORT OF 2 CASES AND COMPLICATIONS IN MANAGEMENT, Journal of dentistry for children, 63(6), 1996, pp. 408
Gingival overgrowth is a known side effect of several seizure, immunos
uppressant and calcium channel-blocker medications. Gingival overgrowt
h is not a reported side-effect of phenobarbital. This case report des
cribes two patients with marked gingival overgrowth who had been medic
ated with phenobarbital exclusively since the initiation of seizure di
sorders. The clinical findings, surgical management, bleeding complica
tions, and recommendations in management are discussed.