Plants produce a wide range of defensive compounds (allomones) to prot
ect themselves from predators and pathogens. Selected allomones have b
een screened against plant parasitic nematodes for a range of activiti
es such as anti-hatching, repellent, nematotoxic, anti-feedant or anti
-virus vectoring activities and inhibition of female development. Plan
t-growth stimulation and anti-nematode activities complementary to hos
t-plant resistance were also studied. Examples are presented of ways i
n which plant-derived compounds can interfere with the life cycles of
nematodes and their close relationships with host plants. The potentia
l of plant-derived compounds in future environmentally benign integrat
ed pest management of nematodes is discussed.