PARVOVIRUS B19 DIAGNOSIS IN PREGNANT-WOMEN - QUANTIFICATION OF IGG ANTIBODY-LEVELS (IU ML) WITH REFERENCE TO THE INTERNATIONAL PARVOVIRUS B19 STANDARD SERUM/

On the basis of the results of a collaborative study the Expert Commit tee on Biological Standardisation of the World Health Organisation has issued an international standard (IS) serum for parvovirus B19 IgG an tibody (NIBSC 93/724). In this study this; IS was used to calibrate an in-house standard serum for reporting the results of parvovirus B19 I gG testing in IU/ml. The IgG titre distribution in 939 pregnant women was determined. These samples were sent to the laboratory for determin ing the immune status to parvovirus B19 following contact with parvovi rus B19 infected individuals or for detecting acute infection in patie nts with symptoms suggestive of parvovirus B19 infection.