PARENTERAL GANCICLOVIR TREATMENT OF ACUTE CMV INFECTION IN THE IMMUNOCOMPETENT HOST

The treatment with ganciclovir of two non-compromised patients who req uired hospitalisation with acute cytomegalovirus (CMV) infection is de scribed. Ganciclovir has rarely been used in such circumstances but, i n four previously reported patients and in the patients described here , a rapid response to therapy was seen. In contrast to previous report s, relatively short courses of treatment (3-5 days) were given to our patients. The drug was well tolerated in each case and may have a role to play in the treatment of severe acute CMV infection in the normal host.