The computed tomographic (CT) appearances are described in five vinyl
chloride workers with hepatic angiosarcoma subsequently confirmed at p
ost-mortem. The tumour was multifocal in four patients. Non-enhanced s
cans were available in four cases showing hypodense masses relative to
background liver. Dynamic scanning during intravenous contrast inject
ion was performed in all five patients showing peripheral or central f
oci of enhancement within the tumour. On delayed post-contrast scans p
erformed in three patients the angiosarcoma became wholly or partly is
odense compared to normal liver. The CT appearances of angiosarcoma of
the liver are non-specific but are consistent with a vascular tumour,
and the differential diagnosis is discussed. Due to the vascularity o
f angiosarcoma, liver biopsy may be hazardous and can be avoided when
there is a history of exposure to vinyl chloride monomer and the CT fi
ndings are consistent with the diagnosis.