The prevalence and significance of microalbuminuria is not well elucid
ated in patients with essential hypertension. In newly detected hypert
ension, its prevalence ranges between 23 and 37% and albuminuria is us
ually well correlated with the level of arterial pressure. Interesting
ly, albuminuria is enhanced in overweight hypertensive patients. Antih
ypertensive treatment has variable influence on albuminuria, and conve
rting enzyme inhibitors, in contrast to other agents, tend to partiall
y correct this abnormality. Whether microalbuminuria represents a pred
ictor of the future development of nephrosclerosis and ultimately rena
l failure, or a predictor of cardiovascular morbidity deserves to be i
nvestigated.