Degradation of air quality in the Space Shuttle environment through ch
emical contamination and high solid-particulate levels may affect crew
performance and health. A comprehensive study of the Shuttle atmosphe
re was undertaken during the STS-40 (Spacelab Space Life Sciences 1) a
nd STS-42 (Spacelab International Microgravity Laboratory 1) missions
to determine the effectiveness of contaminant control procedures by me
asuring concentrations of volatile organic compounds and analyzing par
ticulate matter trapped on air filters. Analysis of volatile contamina
nts showed that the air was toxicologically safe to breathe during bot
h missions with the exception of one period during STS-40 when the Orb
iter Refrigerator/Freezer was releasing noxious gases into the middeck
. Chemical analyses of selected particles collected on air filters fac
ilitated their positive identification. Trace amounts of rat hair and
food particles were found in the STS-40 Spacelab filters; a trace amou
nt of soilless plant-growth media was detected in the STS-42 Spacelab
filter. The low levels of particles released from these Spacelab exper
iments indicate that containment measures were effective.