DETECTION OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-1 PROVIRAL DNA IN THE SALIVA OF AN ADULT T-CELL LEUKEMIA-LYMPHOMA PATIENT USING THE POLYMERASE CHAIN-REACTION
S. Taniguchi et al., DETECTION OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-1 PROVIRAL DNA IN THE SALIVA OF AN ADULT T-CELL LEUKEMIA-LYMPHOMA PATIENT USING THE POLYMERASE CHAIN-REACTION, British journal of dermatology, 129(5), 1993, pp. 637-641
We report a case of adult T-cell leukaemia/lymphoma (ATLL), in whom th
e polymerase chain reaction (PCR) on genomic DNA from saliva demonstra
ted the monoclonal integration of human T-cell lymphotropic virus type
-1 (HTLV-1) proviral DNA in lymphocytes in the saliva. These results p
rovided evidence of the possibility of saliva-borne transmission of HT
LV-1.