BULLOUS PYODERMA-GANGRENOSUM

Pyoderma gangrenosum is a necrotizing, ulcerative process commonly ass ociated with inflammatory bowel disease but also occurring in several other systemic illnesses. When associated with myelodysplastic syndrom es, its clinical appearance is often atypical. We describe a patient w ith severe, refractory bullous pyoderma gangrenosum. At autopsy cardia c involvement was demonstrated, a finding not previously reported. Pat ients with this unusual variant of pyoderma gangrenosum have a grave p rognosis.