POSTOPERATIVE RADIOTHERAPY AFTER PNEUMONECTOMY - IMPACT OF MODERN TREATMENT FACILITIES

Citation
P. Philips et al., POSTOPERATIVE RADIOTHERAPY AFTER PNEUMONECTOMY - IMPACT OF MODERN TREATMENT FACILITIES, International journal of radiation oncology, biology, physics, 27(3), 1993, pp. 525-529
Citations number
16
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
03603016
Volume
27
Issue
3
Year of publication
1993
Pages
525 - 529
Database
ISI
SICI code
0360-3016(1993)27:3<525:PRAP-I>2.0.ZU;2-6
Abstract
Purpose: The present study was undertaken to see how modern treatment facilities, computed tomography (CT)-based treatment planning and line ar accelerator, have modified the results of postoperative irradiation after a pneumonectomy for lung cancer. Methods and Materials: Between 1970-1985, 103 patients were treated in our department after a pneumo nectomy: 50 patients with a T1T2N0 tumor and 53 patients with a T3, N1 or N2 tumor. Three groups were considered: 27 patients had only surgi cal resection, 51 patients were irradiated postoperatively with a Co60 source, and 25 patients were treated using those modern facilities. R esults: The 5-year survival varies from 4% to 31% according to the tum or extent but also to the radiation technique. Patients treated with a Co60 source had a dismal 5-year survival rate (8%) whereas patients t reated with the modern facilities had a 5-year survival rate of 30% si milar to the 31% of the control surgical group including less advanced tumors. Conclusion: Linear accelerator and computed tomography-based treatment planning improved the accuracy of postoperative thoracic irr adiation and allow to deliver high doses to the mediastinum even after a pneumonectomy.