Percutaneous balloon pulmonary valvuloplasty for congenital pulmonary
valve stenosis was performed in 40 adult patients (aged 18 to 56 years
). The duration of follow-up was 24.5 +/- 11.5 months. The peak systol
ic pressure gradient from the right ventricle to the pulmonary artery
decreased from 107 +/- 29 mm Hg to 37 +/- 25 mm Hg immediately after t
he procedure. On follow-up, gradient obtained either by cardiac cathet
erization or Doppler echocardiography was 31 +/- 13 mm Hg. In eight pa
tients with residual gradient after valvuloplasty of >50 mm, the mean
peak systolic gradient decreased from 74.5 +/- 18.3 to 33.5 +/- 13.9 m
m Hg on follow-up. Thus balloon pulmonary valvuloplasty is a safe and
effective procedure for the treatment of adult patients with pulmonic
stenosis; there is a tendency for high residual gradients to regress o
n follow-up.