SYNTHESIS OF (ALPHA,ALPHA-DIFLUOROALKYL)PHOSPHONATES BY DISPLACEMENT OF PRIMARY TRIFLATES

Authors
BERKOWITZ DB EGGEN M SHEN Q SLOSS DG
Citation
Db. Berkowitz et al., SYNTHESIS OF (ALPHA,ALPHA-DIFLUOROALKYL)PHOSPHONATES BY DISPLACEMENT OF PRIMARY TRIFLATES, Journal of organic chemistry, 58(23), 1993, pp. 6174-6176
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
58
Issue
23
Year of publication
1993
Pages
6174 - 6176
Database
ISI
SICI code
0022-3263(1993)58:23<6174:SO(BDO>2.0.ZU;2-F
Abstract
Simple primary alkyl triflates and those derived from several monosacc harides are cleanly displaced by diethyl (lithiodifluoromethyl)phospho nate to provide the corresponding (alpha,alpha-difluoroalkyl)phosphona tes in minutes at -78-degrees-C.