CALCIUM-UPTAKE DURING MITOGENIC STIMULATION OF HUMAN-LYMPHOCYTES - CHARACTERIZATION OF INTRACELLULAR CALCIUM COMPARTMENTS AND DEMONSTRATIONOF THE PRESENCE OF IMMUNOREACTIVE CALRECTICULIN

Authors
MOOKERJEE BK CHAKRABARTI R LEE TP MICHALAK M BALLARD J
Citation
Bk. Mookerjee et al., CALCIUM-UPTAKE DURING MITOGENIC STIMULATION OF HUMAN-LYMPHOCYTES - CHARACTERIZATION OF INTRACELLULAR CALCIUM COMPARTMENTS AND DEMONSTRATIONOF THE PRESENCE OF IMMUNOREACTIVE CALRECTICULIN, Immunological investigations, 22(6-7), 1993, pp. 415-429
Citations number
24
Categorie Soggetti
Immunology
Journal title
Immunological investigations → ACNP
ISSN journal
08820139
Volume
22
Issue
6-7
Year of publication
1993
Pages
415 - 429
Database
ISI
SICI code
0882-0139(1993)22:6-7<415:CDMSOH>2.0.ZU;2-X
Abstract
Phytohemagglutinin (PHA) stimulation of human peripheral blood lymphoc ytes (HPBL) rapidly increases Ca-45(2+) uptake into intracellular pool s. Detectable increase in Ca-45(2+) uptake occurred only on exposure t o mitogenic lectins but not with non-mitogenic lectins. However, intra cellular free Ca2+ concentration [(Ca2+)i] increased comparably on exp osure to either mitogenic or non-mitogenic lectins.