The effect of food deprivation on alcohol self-administration was exam
ined in five women with bulimia nervosa and five healthy controls in a
semi-naturalistic experimental design. In this within-subjects study,
each individual underwent two food-deprived and two non-deprived sess
ions. The deprivation condition consisted of no food or caloric bevera
ges for 19 hours prior to the experimental procedure. On each of the 4
days, subjects watched a 2-hour segment of an epic movie and were per
mitted to drink ad libitum. No differences were observed in the number
of grams of alcohol consumed under deprived and non-deprived for eith
er group. Breath alcohol levels were significantly higher under the no
n-deprived condition despite equivalent amounts of alcohol consumed an
d similar ratings of the subjective sense of tipsiness Bulimic consume
d equivalent calories due to alcohol as control women but significantl
y fewer calories due to non-alcoholic beverages. These results do not
support the hypothesis that food deprivation leads to increased self-a
dministration of alcohol in women.