NUCLEOPHILIC-SUBSTITUTION OF 3-FLUOROSULFONYLOXY CEPHALOSPORINS WITH ORGANOCUPRATES

Authors
ROTH GP PETERSON SA KANT J
Citation
Gp. Roth et al., NUCLEOPHILIC-SUBSTITUTION OF 3-FLUOROSULFONYLOXY CEPHALOSPORINS WITH ORGANOCUPRATES, Tetrahedron letters, 34(45), 1993, pp. 7229-7230
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
45
Year of publication
1993
Pages
7229 - 7230
Database
ISI
SICI code
0040-4039(1993)34:45<7229:NO3CWO>2.0.ZU;2-8
Abstract
3-Fluorosulfonyloxy cephems readily undergo addition-elimination react ions with organocuprates derived from the corresponding Grignard reage nts. This chemistry presents an efficient, cost effective process for the preparation of 3-substituted cephems.