REDUCTION OF ISOQUINOLINE AND PYRIDINE-CONTAINING HETEROCYCLES WITH LITHIUM TRIETHYLBOROHYDRIDE (SUPER-HYDRIDE(R))

Authors
BLOUGH BE CARROLL FI
Citation
Be. Blough et Fi. Carroll, REDUCTION OF ISOQUINOLINE AND PYRIDINE-CONTAINING HETEROCYCLES WITH LITHIUM TRIETHYLBOROHYDRIDE (SUPER-HYDRIDE(R)), Tetrahedron letters, 34(45), 1993, pp. 7239-7242
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
45
Year of publication
1993
Pages
7239 - 7242
Database
ISI
SICI code
0040-4039(1993)34:45<7239:ROIAPH>2.0.ZU;2-K
Abstract
Isoquinolines, quinoline and pyridines are effectively reduced to 1,2, 3,4-tetrahydroisoquinolines, 1,2,3,4-tetrahydroquinolines and piperidi nes respectively with lithium triethylborohydride (Super-Hydride(R)). The mechanism of the reduction was explored by reduction of isoquinoli ne and pyridine with lithium triethylborodeuteride (Super-Deuteride(R) ).