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ITA
ENG
THE 1ST SYNTHESIS OF THE N-GLUCOSYL ANALOG OF THE ANTITUMOR AGENT ETOPOSIDE
Authors
ALLEVI P
ANASTASIA M
CIUFFREDA P
Citation
P. Allevi et al., THE 1ST SYNTHESIS OF THE N-GLUCOSYL ANALOG OF THE ANTITUMOR AGENT ETOPOSIDE, Tetrahedron letters, 34(45), 1993, pp. 7313-7316
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters
→
ACNP
ISSN journal
00404039
Volume
34
Issue
45
Year of publication
1993
Pages
7313 - 7316
Database
ISI
SICI code
0040-4039(1993)34:45<7313:T1SOTN>2.0.ZU;2-O
Abstract
The first synthesis of 1-aminoglucose analogue of the antitumor agent etoposide is accomplished by condensation of 2,3-di-O-trimethylsilyl-b eta-D-glucopyranosylamine with 4-bromo-4-deoxy-4'-demethylepipodophyll otoxin in the presence of Hg(CN)2.