F. Bucher et al., DISTURBANCES IN THE PROOXIDANT - ANTIOXIDANT BALANCE IN THE LIVER OF BULLHEAD (COTTUS-GOBIO L) EXPOSED TO TREATED PAPER-MILL EFFLUENTS, Chemosphere, 27(8), 1993, pp. 1329-1338
The effects of paper mill effluents on the prooxidant-antioxidant bala
nce in the liver of bullhead were studied in fish from a contaminated
river. After the low-water period (theoretical concentration of waste
water 1.7%) the aryl hydrocarbon hydroxylase was strongly induced, glu
cose-6-phosphate dehydrogenase, reduced glutathione and vitamin C were
lower, and catalase was unaltered. Following the high-water period (t
heoretical waste water concentration 0.5%), signs of oxidative stress
were no longer detectable. The risks of oxidative damage due to bioche
mical changes during the low-water period are discussed.