Gastrospirillum hominis is a spiral-shaped bacterium found in the stom
ach. It has been implicated as a possible cause of chronic gastritis.
We report two cases of G. hominis colonization observed in a series of
175 healthy, asymptomatic volunteers investigated for Helicobacter py
lori. None of the volunteers had symptoms or a history of gastrointest
inal disease. Both carriers of G. hominis had histological signs of ch
ronic, active antral gastritis. Multiple tests for H. pylori were nega
tive. The prevalence of this spiral bacterium in healthy, asymptomatic
individuals may be as low as in symptomatic persons.