NEW COMBINATION FOR THE THERAPY OF CANINE OTITIS-EXTERNA-I MICROBIOLOGY OF OTITIS-EXTERNA

In order to compound a new drug combination against canine otitis exte rna (OE), 515 dogs affected with OE were subjected to physical examina tion and microbiological analysis of their ear exudates, OE was erythe matous-ceruminous in 83 per cent and suppurative in 17 per cent of the patient material. Erythematous-ceruminous inflammations were characte rised by severe pruritus and accumulation of brownish, greasy cerumen in the auditory canal, The yeast Malassezia pachydermatis was isolated from the ears of 76 per cent of the dogs, often in combination with S taphylococcus intermedius bacteria, M pachydermatis showed the most se nsitivity, in decreasing order of efficacy, to ketoconazole, econazole , clotrimazole, miconazole and nystatin, S intermedius isolates were m ost sensitive to amoxycillin-clavulanic acid, enrofloxacin, cephalexin and gentamicin. The microorganism most frequently isolated from dogs with suppurative OE was Pseudomonas aeruginosa; in some cases Proteus, Streptococcus and Pasteurella were also isolated. The P aeruginosa is olates showed the highest sensitivity to gentamicin, polymyxin B and t obramycin.